• Autism
  • About Us
  • Ways to Give
    • Participate
      • Toys R Us Canada Play packs
      • World Autism Month
        • Meet Ileana
        • Meet Lindsay
        • Meet Mackenna
        • Meet Daud
        • Meet Griffin
        • Meet Dr. Catherine G.
        • Meet Wanda Deschamps
        • Meet Jackie McMillan
        • Meet Steven Atme
        • Meet Jack Baranoff
        • Meet Olivier St-Amour
      • Autism Speaks Canada Walk
        • marchons
        • Current and Past Ambassadors
      • Autism Speaks Canada bubly Smile Day
      • Autism Speaks Canada Virtual Dog Walk & Auction
      • Game On with Autism Speaks Canada
      • Giving Tuesday
      • Facebook Fundraisers
      • Fundraise Your Way
      • Team Up!
      • One-Time Gifts
      • Monthly Giving
      • Honour Someone Special
      • Support an Event Participant
      • Birthdays with Echoage
      • Estate and Tax Smart Giving
      • Donate a Car
    • Become a Partner
      • Meet Our Partners
        • Gifted Canada
        • Vancouver Foundation
        • McConnell Foundation
        • Azrieli Foundation
        • Scentsy Canada
        • Samsung Canada
        • Randstad
        • Metrocon Ready Mix Corp.
        • PepsiCo
        • dentalcorp
        • Cadillac Fairview
        • Cherry Hill
        • ToysRUs/BabiesRUs
        • Equitable Life of Canada
        • KRG
        • Cineplex
        • Kernels
        • NFP
        • Bank of Montreal
        • A Buyer's Choice
        • Echoage
        • Donate a Car
        • Canadian Heritage - Government of Canada
        • Globe Meats Fresh Market and Grill
        • Nutrience
      • Cash and In-Kind Donations
      • Cause Related Marketing
      • Corporate Teams
      • Event Hosting
      • Matching Gifts
      • Sponsorship
      • Corporate Volunteering
      • Workplace Giving
    • Volunteer
      • Volunteer Stories
    • Merchandise
  • Science, Services & Supports
    • Pandemic Canadian Autism Needs Assessment Results
    • COVID-19 Information and Resources by our Autism Response Team
      • Families & Caregivers Looking for Children Resources
      • Adults on the Spectrum Looking for Resources
      • Virtual Events for Everyone
      • Other Useful Links for Everyone
      • Surveys
    • Science
      • Science News
      • Grant Search
      • Apply for Grants or Fellowships
      • MSSNG
      • Autism Treatment Network
        • ATN@Work
      • Participate In Research
        • Post-Doctoral Research Fellowship in Developmental Pathways in Autism Spectrum Disorder (ASD)
        • Caring for the Caregiver
        • Kids Brain Health Network
        • Family Participation in Research
        • It Takes Brains
        • Interactive Autism Network
        • Holland Bloorview Kids Rehabilitation Hospital
        • University of Toronto
        • York University
      • Science Blogs
      • Science Digest
        • Spring 2018
    • Family Services
      • Family Services Community Grants
        • FSCG Grant Review Volunteers
      • Family Services Special Targeted Initiatives Grants
        • Pacific Autism Family Network (PAFN)
        • Integrated Services for Autism & Neurodevelopmental Disorders (ISAND)
      • Family Services Partnerships
        • Family Services Community Grants
        • Tablet Program
        • Sensory Friendly Screenings
        • Sensory Friendly Santa – Enjoy a Virtual Visit with Santa!
      • Worktopia
    • Resources
      • Apps
      • Technology Central
      • Going Out to Eat
      • Health & Wellness
      • Bullying
      • Wandering
      • Templates for Personalized Teaching Stories
      • Community Connections
      • My Job Chart
      • Resource Library
      • Glossary of Terms
      • Accessing Government Services
      • Your Religious Community
    • ASC Connect
  • News, Media Request & Contact Us
    • News
      • News
        • Autism Speaks Canada joins disability groups calling for priority access to COVID vaccine for people with autism
        • Autism Speaks Canada's statement about the Alek Minassian case and its misrepresentation of autism
        • ASC, CASDA, and MacART come together to present the Pandemic Canadian Autism Needs Assessment Survey Report
        • SickKids researchers find new genes and variations linked to autism using Autism Speaks' MSSNG data
        • Toys R Us Canada in partnership with Autism Speaks Canada is proud to launch discounted play packs
        • Olivier, Our Dog Walk Ambassador Is in the News
        • Covid-19, We Are in This Together
        • Advocates and researchers discuss solutions to reduce autism health care disparities
        • Justin Trudeau Announces Endorsement for Development of a National Autism Strategy
        • Join Us in Creating a Brighter Life on the Spectrum
        • Media Advisory: Trudeau Is Only Major Party Leader Not Committed To A National Autism Strategy
        • Large family-based study finds 80 percent of autism risk is from inherited genes
        • Autism Speaks Canada is excited to announce their new partnership with MKM group and Shattered Dreams Esports
        • Autism Speaks awards more than $4.7 million for autism research
        • Autism Speaks Canada is excited to announce their new partnership with bubly sparkling water beverage
        • Six Autism Speaks studies on 2018 list of top advances in autism
        • Senator Munson's Visit to McMaster May 21, 2019
        • Community Connections Inspire Samsung Canada and Autism Speaks Canada
        • Autism Speaks Canada's annual Walk comes to Waterloo this Sunday
        • Autism Speaks Canada's annual Walk comes to Toronto
        • Autism Speaks' MSSNG project reaches 10,000-genome milestone
        • The Canada Council for the Arts Reveals the 2019 Killam Program Winners
        • Light It up Blue With Autism Speaks Canada
        • Response to the Ontario Autism Program (OAP)
        • DNAstack and Autism Speaks® Announce Collaboration to Accelerate Scientific Discovery on One of the World's Largest Autism Genome Databases
        • Autism Speaks launches $1.5 million funding opportunity for treatment studies
        • Whole genome sequencing reveals new type of genetic influence on autism
        • Understanding the 2018 National Autism Spectrum Disorder Surveillance System (NASS) Report
        • Autism Speaks releases new strategic plan for science
        • World's largest autism genome databank adds more than 2,000 sequences
        • Support Rooted in Desire to Improve Lives
        • Samsung Canada, Silken Laumann and Autism Speaks Canada Invite Canadians to Learn the Love Spectrum
        • Your ATN@Work: Treating anxiety in children and teens with autism
        • Your ATN@Work: Recognizing anxiety in children and teens with autism
        • Expanding Service Options for Children and Youth with Autism
        • Tracing autism's trajectories could help explain its diversity
        • Gathering MSSNG Insights on Autism
        • Thomas Frazier to join Autism Speaks as Chief Science Officer
        • Study Aims to Crack Autism Code
        • Ontario Ombudsman has released the report, Nowhere to Turn
        • The Autism World: Choosing In
        • The Government of Canada wants your input as they develop accessibility legislation
        • The University of Windsor is looking for fathers across Canada
        • Autism Speaks MSSNG study expands understanding of autism's complex genetics.
        • Choices Markets to Host Fundraiser to Raise Awareness and Funds for Autism Speaks Canada
        • The Sinneave Family Foundation and Autism Speaks Canada Partner With Organizations Across Canada to Improve Employment Futures for Individuals With Autism Spectrum Disorder
        • Ontario Providing More Supports For Children With Autism
        • Autism Speaks ATN/AIR-P researchers present studies at IMFAR
        • More than 5,000 whole genome sequences now available for research into autism subtypes and personalized treatments
        • Spokesperson for the Minister answers FAQ's regarding Ontario Autism Program
        • Giving children roots and wings: the struggle to understand autism.
        • Information for families about changes to autism services for children & youth
        • Ontario Budget Announcement
        • Ontario government announces new Ontario Autism Program with investment of $333 million over the next five years
        • 'Aging Out': What happens when children with ASD get older?
        • PBS NewsHour Looks at MSSNG Genome Project
        • New Canada-U.S. Partnership Paves the Way for International Collaborations in Autism Research
        • Autism Speaks Launches MSSNG Portal for Open-Access Genomics Research
        • Choices Markets to Host Fundraiser to Raise Awareness and Funds for Autism Speaks Canada
        • Kinetic Sand Teams Up with Autism Speaks to Raise Awareness
        • Learning to better understand autism spectrum disorder
        • 2014 Family Services Community Grants Announcement
        • Cineplex and Autism Speaks to offer Sensory Friendly Screenings
        • Diversity in Developmental Trajectories in Kids with Autism Spectrum Disorder
        • Largest genome sequencing study finds surprises: siblings' autism may have different genetic causes
COVID-19 Information and Resources
  • EN
    • FR
  • A A
  • Accessibility
  • Donate Now
 
Autism Speaks EN Autism Speaks EN
  • Autism
  • About Us
  • Ways to Give
  • Science, Services & Supports
  • News, Media Request & Contact Us
  1. Home
  2. News, Media Request & Contact Us
  3. News
  4. News
  5. Autism Speaks' MSSNG project reaches 10,000-genome milestone
  • News
    • Autism Speaks Canada joins disability groups calling for priority access to COVID vaccine for people with autism
    • Autism Speaks Canada's statement about the Alek Minassian case and its misrepresentation of autism
    • ASC, CASDA, and MacART come together to present the Pandemic Canadian Autism Needs Assessment Survey Report
    • SickKids researchers find new genes and variations linked to autism using Autism Speaks' MSSNG data
    • Toys R Us Canada in partnership with Autism Speaks Canada is proud to launch discounted play packs
    • Olivier, Our Dog Walk Ambassador Is in the News
    • Covid-19, We Are in This Together
    • Advocates and researchers discuss solutions to reduce autism health care disparities
    • Justin Trudeau Announces Endorsement for Development of a National Autism Strategy
    • Join Us in Creating a Brighter Life on the Spectrum
    • Media Advisory: Trudeau Is Only Major Party Leader Not Committed To A National Autism Strategy
    • Large family-based study finds 80 percent of autism risk is from inherited genes
    • Autism Speaks Canada is excited to announce their new partnership with MKM group and Shattered Dreams Esports
    • Autism Speaks awards more than $4.7 million for autism research
    • Autism Speaks Canada is excited to announce their new partnership with bubly sparkling water beverage
    • Six Autism Speaks studies on 2018 list of top advances in autism
    • Senator Munson's Visit to McMaster May 21, 2019
    • Community Connections Inspire Samsung Canada and Autism Speaks Canada
    • Autism Speaks Canada's annual Walk comes to Waterloo this Sunday
    • Autism Speaks Canada's annual Walk comes to Toronto
    • Autism Speaks' MSSNG project reaches 10,000-genome milestone
    • The Canada Council for the Arts Reveals the 2019 Killam Program Winners
    • Light It up Blue With Autism Speaks Canada
    • Response to the Ontario Autism Program (OAP)
    • DNAstack and Autism Speaks® Announce Collaboration to Accelerate Scientific Discovery on One of the World's Largest Autism Genome Databases
    • Autism Speaks launches $1.5 million funding opportunity for treatment studies
    • Whole genome sequencing reveals new type of genetic influence on autism
    • Understanding the 2018 National Autism Spectrum Disorder Surveillance System (NASS) Report
    • Autism Speaks releases new strategic plan for science
    • World's largest autism genome databank adds more than 2,000 sequences
    • Support Rooted in Desire to Improve Lives
    • Samsung Canada, Silken Laumann and Autism Speaks Canada Invite Canadians to Learn the Love Spectrum
    • Your ATN@Work: Treating anxiety in children and teens with autism
    • Your ATN@Work: Recognizing anxiety in children and teens with autism
    • Expanding Service Options for Children and Youth with Autism
    • Tracing autism's trajectories could help explain its diversity
    • Gathering MSSNG Insights on Autism
    • Thomas Frazier to join Autism Speaks as Chief Science Officer
    • Study Aims to Crack Autism Code
    • Ontario Ombudsman has released the report, Nowhere to Turn
    • The Autism World: Choosing In
    • The Government of Canada wants your input as they develop accessibility legislation
    • The University of Windsor is looking for fathers across Canada
    • Autism Speaks MSSNG study expands understanding of autism's complex genetics.
    • Choices Markets to Host Fundraiser to Raise Awareness and Funds for Autism Speaks Canada
    • The Sinneave Family Foundation and Autism Speaks Canada Partner With Organizations Across Canada to Improve Employment Futures for Individuals With Autism Spectrum Disorder
    • Ontario Providing More Supports For Children With Autism
    • Autism Speaks ATN/AIR-P researchers present studies at IMFAR
    • More than 5,000 whole genome sequences now available for research into autism subtypes and personalized treatments
    • Spokesperson for the Minister answers FAQ's regarding Ontario Autism Program

Donate Landing photo

COVID-19 Information and Resources

Autism Speaks' MSSNG project reaches 10,000-genome milestone

World’s largest autism whole-genome database a beacon to developing new solutions for individuals with autism and their families

NEW YORK (May 6, 2019) – Autism Speaks’ groundbreaking MSSNG project has reached its initial goal of sequencing more than 10,000 whole genomes of individuals with autism and their family members in the latest update to its signature genetics program, creating the world’s largest open-source precision medicine database specific to understanding autism.

“Having 10,000 whole-genome sequences on one free, open-source platform gives researchers with diverse questions from around the world a powerful resource to better understand the genetics of autism and how they relate to each person’s unique strengths and challenges,” said Thomas Frazier, Ph.D., chief science officer for Autism Speaks. “MSSNG is central to our goal to rapidly develop ways to personalize care for people with autism.”

The 10,000-genome dataset, which continues to grow, goes live in June 2019 in an advanced database, a critical milestone in ensuring that more genetic variations – and more types of autism – are represented in research analysis and results.

“We know there are many subtypes of autism. The more data we include related to different types of autism in each research study, the more inclusive the results will be, fueling a flow of discoveries,” said Stephen Scherer, Ph.D., MSSNG research director. Dr. Scherer directs the Centre for Applied Genomics at The Hospital for Sick Children (SickKids) in Toronto, where the genome sequencing is conducted.

Launched in 2015, the MSSNG database started as a collaboration with SickKids and Google. To date, MSSNG’s cloud-based computing system is freely sharing data globally in 58 institutions across 16 countries producing transformational autism research studies. This has included 18 newly identified autism risk genes that include de novo mutations, as well as changes in non-gene encoding regions.

Autism Speaks and SickKids are joined by critical partners Verily and DNAstack, which are both leaders in genomics engineering. Their contributions of cutting-edge technology and resources make MSSNG one of the most advanced autism genetic databases.

“MSSNG's rich data, powerful software and broad researcher access help close gaps in the world's understanding of autism," said David Glazer, engineering director at Verily. “Sequencing 10,000 genomes from affected families is an exciting milestone in our efforts to collect, organize and activate health information.”

Technological features from these firms align MSSNG data to global standards, allowing researchers to access multiple large datasets from one interface and give deeper insight into the underpinnings of autism. These features promote responsible open science that can accelerate discoveries to find information and solutions for individuals and families seeking help.

“Sharing data is one of the best ways to accelerate our understanding of genetically complex disorders like autism,” said Dr. Marc Fiume, CEO of DNAstack and co-chair of the Discovery Work Stream for the GA4GH. “MSSNG is pioneering new methods in open science that will make data more findable, accessible and useful. MSSNG will have an enormous impact on open science, far beyond autism, for years to come.”

With this update, MSSNG also will join the Beacon Network, a global search engine for finding genetic variations, allowing autism researchers to easily find similar data. Just as critical, the MSSNG beacon will allow scientists from other disciplines to find similar data they are studying, thus bringing new researchers and insights into the autism field.

Autism Speaks co-founded Autism Sharing Initiative (ASI) to catalyze worldwide sharing of data in autism, and the ASI was recently selected as a Driver Project of the Global Alliance for Genomics and Health (GA4GH).

“ASI encourages research institutions to build technological and sociological bridges to other whole-genome autism datasets. Data sharing helps accelerate discovery,” said Dean Hartley, senior director of genomic discovery at Autism Speaks and a co-lead of the ASI project.

The MSSNG project is made possible by the ongoing support of individual donors and foundations, whose generosity has been a catalyst for achieving a greater understanding of autism. In particular, the visionary leadership of the Board of Autism Speaks, particularly founder Bob Wright, led to the organization's historic investment in MSSNG. Private philanthropy via Autism Speaks has funded nearly $16 million in the MSSNG Genomic Initiative.

To apply for access to MSSNG, visit mss.ng.

--

About Autism

Autism, or autism spectrum disorder, refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication. We now know that there is not one autism but many subtypes, and each person with autism can have unique strengths and challenges. A combination of genetic and environmental factors may influence the development of autism, and autism often is accompanied by medical issues such as GI disorders, seizures and sleep disturbances. Autism affects an estimated 1 in 66 children in Canada.

Media Contacts:

Sarah Ahmed: sarahahmed@autismspeakscan.ca

Contact Us
  • 2450 Victoria Park Avenue, Unit 400
    Toronto, ON M2J 4A2
  • Local: 416-362-6227
  • Toll Free: 1-888-362-6227
  • Fax: 416-362-6228
  • About
  • ASC Connect
  • Get Involved
  • Science, Services & Resources
  • Ways to Give
  • News
  • Media Request & Contact Us
Our Partners
Nutrience
Globe Meats Fresh Market and Grill
Canadian Heritage - Government of Canada
Donate a Car
Echoage
A Buyer's Choice
Bank of Montreal
NFP
Kernels
Cineplex
KRG
Equitable Life of Canada
ToysRUs/BabiesRUs
Cherry Hill
Cadillac Fairview
dentalcorp
PepsiCo
Metrocon Ready Mix Corp.
Randstad
Samsung Canada
  • © 2021 Autism Speaks Canada
  • Site Map
  • Privacy Policy